Disease Vault

Clinical & Medical Disease Vault

Explore thousands of diseases with authoritative clinical information from WHO, CDC, NIH, and international medical guidelines. Every condition features an interactive journey from diagnosis to treatment.

300 Diseases
26 Specialties
12 Sources

Browse by Specialty

Oncology

Oncology C41.9

Ewing Sarcoma

A highly aggressive pediatric bone and soft tissue cancer characterized by small round blue cells and a t(11;22) translocation, requiring intensive systemic and local therapy.

Hematology & Oncology C91.40

Hairy Cell Leukemia

A rare, slow-growing blood cancer where B-cells develop 'hairy' projections, causing an enlarged spleen and low blood counts, highly curable with specific chemotherapy.

Hematology & Oncology C96.21

Systemic Mastocytosis

A rare clonal blood disorder where abnormal mast cells accumulate in the bone marrow and internal organs, releasing histamine and other chemicals that cause severe allergic-like symptoms and potential organ damage.

Hematology & Oncology D47.1

Primary Myelofibrosis

A blood cancer where the bone marrow becomes scarred and fibrotic, forcing the spleen and liver to take over blood production, resulting in profound anemia and a massively enlarged spleen.

Oncology

Chondrosarcoma

A malignant bone cancer that produces cartilage, typically affecting older adults and requiring surgical removal due to resistance to chemo and radiation.

Hematology & Oncology C92.40

Acute Promyelocytic Leukemia

A highly curable but initially deadly leukemia subtype marked by severe bleeding (DIC) and driven by a genetic mutation (t(15;17)) treated with a Vitamin A derivative.

Oncology

Choriocarcinoma

An aggressive, highly curable cancer of the placenta that can occur after any pregnancy, characterized by very high hCG levels and rapid spread to the lungs.

System Notice

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